Determination of Butamyrate Citrate in Cough Preparations by Derivative UV Spectrophotometry and High Performance Liquid Chromatography

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Determination of butamyrate citrate in cough preparations by derivative UV spectrophotometry and high performance liquid chromatography.

Derivative spectrophotometric procedures and an isocratic high performance liquid chromatographic method for the determination of butamyrate citrate (Sinecod, Safarol) in cough syrups have been developed. In the spectrophotometric method, direct measurement of the drug at its absorption maxima is impossible because of interference from different absorbing excipients. Extraction of butamyrate ci...

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ژورنال

عنوان ژورنال: Analytical Sciences

سال: 2003

ISSN: 0910-6340,1348-2246

DOI: 10.2116/analsci.19.563